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br Discussion br Conclusion br
2018-11-06
Discussion Conclusion Author role form Aforementioned authors have made a direct and substantial contribution to the following areas: Acknowledgment Introduction Depression following a traumatic betaxolol injury (TBI) is a severe complication. The incidence of posttraumatic depressio
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In the present study there is
2018-11-06
In the present study, there is apparently no compensatory mechanism in visceral organs in order to overcome STZ induced oxidative stress. Reduced activities of SOD and CAT in liver, kidney and heart have been observed during diabetes. SOD is vital defence enzyme which catalyses the dismutation of su
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Previously we demonstrated that injured kidney tissues can i
2018-11-06
Previously, we demonstrated that injured kidney tissues can induce bone marrow stromal metforman to differentiate into renal tubular epithelial-like cells in vitro and in vivo (Qian et al., 2008). However, another work reported that the beneficial effects of BMSCs are primarily mediated by complex
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sulfanilamide In the present study we examined
2018-11-06
In the present study, we examined the above-mentioned properties of MSC-derived exosomes to limit cell death after myocardial I/R injury in vivo. We show that intact exosomes directly target cardiac sulfanilamide to reduce infarct size. Furthermore, we demonstrate that, in line with our in vitro dat
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Human iPSC lines are usually produced from
2018-11-06
Human iPSC lines are usually produced from fibroblasts isolated from skin biopsies, a traumatic invasive procedure demanding local anesthesia and medical follow-up. Hair follicle (HF) plucking, however, is simple, painless and a non-invasive alternative procedure. In the genuine study demonstrating
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br List of abbreviations and conventions for paper AP SSEA
2018-11-06
List of abbreviations and conventions for paper AP+ SSEA4+-Stage Specific Embryonic Antigen 4 Disclosure of potential conflicts of interest Acknowledgments The authors thank Miss Heidi Mjoseng for help with tissue culture during the course of this project. This project was supported by co
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An approach that has shown promise for answering these types
2018-11-06
An approach that has shown promise for answering these types of questions in other stem cell systems, and is becoming increasingly feasible with advanced computing power and improved tracking algorithms, is long-term in vitro imaging of individual stem and progenitor cells (Schroeder, 2011). Long-te
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Generally histone modifications facilitate protein protein i
2018-11-06
Generally, histone modifications facilitate protein–protein interactions with effector proteins or readers. Bromodomains interact with acetyl-lysines, while chromodomains, plant homeodomains (PHD), and others associate with methyl-lysines. Interestingly, H2AZ-containing nucleosomes associate with se
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A key mechanism whereby macrophages may affect tissue
2018-11-06
A key mechanism whereby macrophages may affect tissue repair and regeneration is by instructing the stem cell niche by paracrine mechanisms. In the mouse skeletal muscle injury model, macrophage-derived paracrine factors promote satellite cell survival, proliferation and differentiation in vitro and
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LY2584702 DNA fragmentation is an essential component
2018-11-06
DNA fragmentation is an essential component of PCD. Of several nucleases that were tested for their involvement in charontosis, EndoG emerged as a likely candidate, although a role for CAD cannot be discounted due to the degradation of ICAD observed 44 h after ETO treatment. EndoG is activated in LY
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For the reproducible neuronal differentiation of hiPSCs a de
2018-11-06
For the reproducible neuronal differentiation of hiPSCs a desirable beneficial step is the establishment of a self-renewable neuronal precursor cell (NPC) line (Falk et al., 2012; Marchetto et al., 2010). Such NPCs can be expanded extensively and subsequently differentiated to a defined neuronal pop
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br Conclusion While our in vivo data
2018-11-06
Conclusion While our in vivo data show that Nilotinib blocks fibrogenesis in the context of skeletal muscle regeneration, our in vitro model provides evidence that mesenchymal progenitor mg115 prompt the expansion of tissue-specific stem cells, strengthening the notion that fibrogenic cell activi
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estrone br Experimental Procedures br Author Contributions
2018-11-05
Experimental Procedures Author Contributions Acknowledgments We are grateful to Dr. Makoto Tachibana for providing mouse TT2 and 248-5 ESCs. This research was supported by the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT and Future Planning (no. 2012M3A
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If we apply the Jacobi Anger expansion
2018-11-05
If we apply the Jacobi–Anger expansion then the real part of the expressions (6) takes the form where (μ) is the nth-order Bessel function; As can be seen from Eq. (7), the spectrum of the frequency-modulated wave is symmetric in frequency: and is not limited. However, for n ≫ μ, the Bessel fun
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br Introduction Studying the temperature dynamics of the
2018-11-05
Introduction Studying the temperature dynamics of the mechanical properties of buy RGFP966 is important for solving the problems of cryobiology, a field concerned with the behavior of cells and tissues at low temperatures [1,2]. These properties of the plasma membrane influence the mechanism beh
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