• In the present study we

  2018-11-08

  

  In the present study, we have used a set of OSCC cell lines and isolated the putative stem cell fraction (CD44highCD24low) along with CD44highCD24high and CD44lowCD24high (non-stem) sub-populations. These populations were subjected to various molecular and cellular assays to determine whether CD24 h

• Indeed both hAT MSC and hiPS

  2018-11-08

  

  Indeed, both hAT-MSC and hiPS-MSC baACL implants, when validated in a swine ACL excision model, resulted in proper ACL tissue formation. In the osseous zones, both in the tibia and the femur, the fibres of the biomaterial were surrounded by newly formed tissue that was encapsulated within mature bon

• Differentiation potential of the MMD ISCH iPSC line was

  2018-11-08

  

  Differentiation potential of the MMD ISCH#6 iPSC line was assessed by Embryoid Body assay. Differentiated 14-day old cultures exhibited the presence of β3-Tubulin (ectoderm), α-SMA (mesoderm) and TROMA-1 (endoderm) immunopositive mtor pathway (Fig. 2A), thus confirming the pluripotent nature of the

• br Material methods br Results br

  2018-11-08

  

  Material & methods Results Discussion Acknowledgements We thank Melissa Carballosa-Gautam in the Miami Project to Cure Paralysis Imaging Core. This design, experimentation, data analysis and manuscript writing was supported by the Miami Project to Cure Paralysis; NIH/NINDS (DJL: NS049545

• We herein show that simple supplementation with

  2018-11-08

  

  We herein show that simple supplementation with doxycycline greatly improves both hESC/iPSC viability and self-renewal. In practice, doxycycline dramatically enhances hESC/iPSC expandability, and the effects continue for long time periods. The effects of doxycycline are mediated by direct activation

• br Experimental Procedures br Author

  2018-11-08

  

  Experimental Procedures Author Contributions Acknowledgments Introduction Recently, substantial progress has been made to elicit organogenesis in 3D culture (Antonica et al., 2012; Huch et al., 2013; Liu et al., 2010; Sato et al., 2009; Spence et al., 2011). In the neural lineage, embryo

• cmv virus Here we sought to identify new druggable therapeut

  2018-11-08

  

  Here, we sought to identify new druggable therapeutic targets for GBM. We combined transcriptome expression profiling and loss-of-function approaches to identify human kinases that play differential roles in PN and/or MES GSCs. Using a human kinome-wide lentiviral shRNA library, we identified 82 can

• PARK is a ubiquitously expressed protein and

  2018-11-08

  

  PARK2 is a ubiquitously expressed protein, and its ubiquitination of outer mitochondrial membrane is a prerequisite step in mitophagy-mediated removal of damaged mitochondria. However, PARK2 abnormalities in adenosine deaminase other than neurons fail to display the selective loss of a particular po

• br Materials and methods br Results br Discussion

  2018-11-08

  

  Materials and methods Results Discussion Primary cells originating from human dental pulp tissue are heterogeneous in that stem cells, various progenitors, and differentiated cells are mixed in culture. The ratio of stem cells is also different in primary culture from pulp tissue obtained f

• br Conclusions The following are the supplementary data

  2018-11-08

  

  Conclusions The following are the supplementary data related to this article. Conflict of interest Acknowledgements This work was supported by The Danish Cancer Society (R.C. Grant number DP07024); Kgl. Hofbundtmester Aage Bang Fund (Grant number 55-07/08); Karen Elise Jensen Fund; Karen K

• Mechanistically SUMO depletion may enhance iPSC

  2018-11-08

  

  Mechanistically, SUMO2 depletion may enhance iPSC formation by derepressing epigenetically silenced pluripotency loci (Poleshko et al., 2014; Yang et al., 2015) as well as histone and protein biosynthesis genes important for cellular growth and proliferation (Neyret-Kahn et al., 2013). Consistently,

• Given the wide array of variables related to violence

  2018-11-07

  

  Given the wide array of variables related to violence, we realize that we could include more covariates. However, the main objective of this research is not to find all possible explanations for the interiorization of violence. Rather, this research\'s objectives are more modest: to empirically test

• The first KLS episode is generally preceded by an

  2018-11-07

  

  The first KLS episode is generally preceded by an event associated with the beginning of the symptoms, more commonly an infection, alcohol ingestion, sleep deprivation, stress, physical exhaustion, travels, naltrexone hcl trauma, surgeries with local or general anesthesia, lactation, menstruation a

• In each report the efficacy of hygienic precautions has been

  2018-11-07

  

  In each report, the efficacy of hygienic precautions has been >75%. Given the ease and effectiveness of this intervention it is appropriate that CMV education and hygienic precautions be implemented clinically. All pregnant women with frequent contact with a child purchase URMC-099 to CMV only). If

• The following are the supplementary

  2018-11-07

  

  The following are the supplementary data related to this article. Author Contributions Conflicts of Interest Acknowledgements/Funding Rosa26-mTmG mice were kindly donated by Dr. Nan Tang (National Institute of Biological Sciences, Beijing, China). This work was supported by the National Na

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