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br Methods br Results br Discussion Adiponectin is
2023-10-23
Methods Results Discussion Adiponectin is naturally expressed and secreted exclusively from adipocytes, and adiponectin levels and its isoforms in circulation have recently been reported to highly associate with human coronary artery disease (CAD) [46], [47], [48], [49], these studies clear
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In summary the role of
2023-10-23
In summary, the role of 5-HT and different types of 5-HTRs in gating plasticity induction in neocortical circuits remains unclear, with variable and seemingly contradictory effects reported for LTP induction in cortical sensory fields (e.g., V1, enhanced LTP: Inaba et al., 2009, Kojic et al., 1997,
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Glucose permeability studies demonstrated a high glucose flu
2023-10-21
Glucose permeability studies demonstrated a high glucose flux through the SF films used in the present work. Recent diffusion studies, including small molecular drugs and oxygen permeation through SF membranes [32], further support the quality of SF and its possible application as a material for bio
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br Methods br Transparency document br Introduction Epinephr
2023-10-21
Methods Transparency document Introduction Epinephrine (EP) is a critical hormone and catecholamine neurotransmitter in nervous system of mammals.1, 2, 3 It has been known to accelerate and regulate heartbeat, blood pressure, bronchodilation, mydriasis, blood sugar and lipolysis, and can he
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br ASK in Huntington s disease and other polyglutamine disea
2023-10-21
ASK1 in Huntington's disease and other polyglutamine diseases The polyglutamine (polyQ) diseases are a group of inherited neurodegenerative disorders caused by the expansion of cytosine-adenine-guanine (CAG) trinucleotide repeats in the coding regions of specific genes, leading to the production
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(-)-epicatechin The current results also demonstrated tenden
2023-10-21
The current results also demonstrated tendencies toward decreased serum Aβ40 levels and increased Aβ42 levels during the 1-year follow-up. These tendencies are consistent with the results of a previous study that evaluated Aβs in the CSF of patients with late-life depression (Pomara et al., 2016). T
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Previous studies have demonstrated that synaptic AMPARs
2023-10-21
Previous studies have demonstrated that synaptic AMPARs can differ greatly in their mobility; some rapidly and constitutively Aloperine in and out of the synaptic membrane, while others remain somewhat stable in the synaptic membrane (Luscher et al., 1999, Luthi et al., 1999). We find that mGluR- an
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As regards feeding the ability to dissipate surplus energy
2023-10-20
As regards feeding, the ability to dissipate surplus energy in the form of heat is beneficial for animals if the protein concentration in the food is low, since it allows them then to meet the adequate protein intake requirement without getting fat. Some of the major dietary activators of the AHR ar
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The same applies also to intermediate
2023-10-20
The same applies also to intermediate , formally obtained by elimination of the R substituent from compound . If compared to the thienopyrimidine derivatives (series , C), the thieno[3,2-]pyridazin-5(4H)-ones – explored herein seem to maintain similar size and shape and also analogue structural char
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br Author contributions br Competing interests br Transparen
2023-10-20
Author contributions Competing interests Transparency document Acknowledgments This research was funded by a TOP ZonMW grant (40-00812-98-10054) to R.O.E., a DFG grant (KR4391/1-1) and IZKF Erlangen grant (J36) to A.K. and supported in part by Centro de Investigación Biomédica en Red de
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br Introduction The process of mitosis is
2023-10-20
Introduction The process of mitosis is highly complex and tightly regulated. This phase of the am 580 australia resulted in two identical daughter cells. The aurora kinases (aurora A, B, and C) are a family of three highly homologous serine-threonine protein kinases that play a key role in regul
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Xylazine HCl br Regulation of V ATPase assembly in
2023-10-20
Regulation of V-ATPase assembly in response to changes in amino Xylazine HCl levels A central regulator of cell growth and metabolism is mTORC1 [38]. mTORC1 integrates signals from nutrient availability and growth factor receptors to control such processes as protein and lipid synthesis and auto
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AMPK is a cellular energy sensor that is
2023-10-20
AMPK is a cellular energy sensor that is phosphorylated in response to high intracellular ADP levels to increase GLUT4 translocation into the cell, and subsequently, increase intracellular glucose levels to provide substrate to replenish ATP levels [25]. In metabolic syndrome, sequestration of plasm
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It has been well established that shortly
2023-10-20
It has been well established that shortly after systemic inflammation, NADPH oxidase and iNOS activity were increased in the Idoxuridine and lead to overproduction of reactive oxygen species (ROS) and NO [66]. Moreover, previous studies indicated that Ang II induced an increased level of NADPH oxida
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Although our sample size is not
2023-10-20
Although our sample size is not enough to conclude that there is no great genetic variation of the AR gene in most New World monkeys, it would be reasonable to state that the microsatellite region in the exon 1 of the androgen receptor gene of New World monkeys (platyrrhine) is relatively shorter th
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