• In the nearly years since the

  2018-11-05

  

  In the nearly 18years since the clevidipine investigational new drug application was filed, our understanding of the structure, tissue distribution and molecular biology of the l-type calcium channels (LTCC) has evolved dramatically (Zuccotti et al., 2011; Abernethy and Soldatov, 2002). The CaV-α-1

• Statistical comparisons between PSG and actigraphy

  2018-11-05

  

  Statistical comparisons between PSG and actigraphy measures obtained from either the original or spline-modified data were performed using several methods: (1) Sleep summary measures obtained from the wrist and hip actigraphy recordings were compared with mean PSG values using a nonparametric Wilcox

• br Sleep and arousal in Parkinson s disease PD

  2018-11-05

  

  Sleep and arousal in Parkinson׳s disease (PD) PD is characterized by a variety of symptoms, which include 3–7Hz resting tremor, rigidity, postural and gait abnormalities, akinesia, and bradykinesia [1]. In addition, a number of other symptoms are present, including abnormal reflexes as well as hi

• Recent developments support the model of CFS

  2018-11-05

  

  Recent developments support the model of CFS as a multisystem illness with symptoms that are due to gastrointestinal and neurotoxic features, on a background of immunological dysfunction. Importantly, discoveries in recent years reinforce the idea that CFS is associated with imbalances in intestinal

• It has however to be taken into account

  2018-11-05

  

  It has, however, to be taken into account that in the present study the measure of sleep duration was exclusively subjective. It is known that sleep time misperceptions are common among subjects with sleep difficulties, particularly insomnia, with a however broad continuum between substantial under-

• br Material and methods br Results

  2018-11-05

  

  Material and methods Results Mean of the total score of CISQ was 15.78±8.47, in asymptomatic subjects CISQ had a mean total score of 6.34±3.29, PSQI in asymptomatic subjects was 5.66±2.47. Differences between average in the CISQ of sample from Xalapa City-Mexico City and from the Clinic of Sle

• br Acknowledgements The research work

  2018-11-05

  

  Acknowledgements The research work has been fully supported by the Higher Education Commission, Pakistan with Support initiative Grant No. IRSIP 21 Ps 04. I would like to thank the Department of Applied sciences of UWE, Bristol,UK for providing access to their lab facilities. Introduction Th

• br Experimental section br Results and discussion Building u

  2018-11-05

  

  Experimental section Results and discussion Building upon our previous work, we developed a water-stable sensor using rGO as the semiconducting channel material and Au NPs as the modular attachment points for immobilizing the probes [7]. This sensor enabled real-time sensing for in situ underw

• For HCC the second leading

  2018-11-03

  

  For HCC, the second leading cause of cancer death worldwide, there is a lack of effective drugs. The only approved drug, sorafenib, has modest survival benefits (Llovet et al., 2008; Abou-Alfa et al., 2006; Cheng et al., 2009). Immunotherapy has been considered as an effective approach for cancer tr

• Es el primer modelo de crecimiento macroecon mico que incorp

  2018-11-03

  

  Es el primer modelo de crecimiento macroeconómico que incorpora el papel de la tecnología en una función de producción. Durante muchos años, este modelo constituiría el marco analítico par excellence a partir del cual se estudiaría el crecimiento económico. A pesar de ser un modelo que incorpora el

• Specifications table br Value of the data br

  2018-11-03

  

  Specifications table Value of the data Experimental design, materials and methods The digital camera was attached to light transmission microscope with 10× objective magnification and no eye pieces. The blood smear has been illuminated by 50W halogen lamp and the image focused by normal micro

• br Data This data article includes the N

  2018-11-03

  

  Data This data article includes the N- and O-glycome of MKN45 cells and assesses the glycosylation alterations induced by ST3GAL4 overexpression. In addition, we provide the data on the proteins with significant increased sialylated N-glycans upon ST3GAL4 overexpression. Experimental design, m

• Funding from the German Federal Ministry

  2018-11-03

  

  Funding from the German Federal Ministry of Education and Research (BMBF) supported parts of this study (Funding code FKZ 16I1619). The Leibniz Center for Agricultural Landscape Research (ZALF) is institutionally funded by the Federal Ministry of Food and Agriculture (BMEL) and the Ministry for Scie

• br Ethic approval br Acknowledgments This work was supported

  2018-11-03

  

  Ethic approval Acknowledgments This work was supported by the Karlsruhe Institute of Technology (KIT), the Deutsche Forschungsgemeinschaft (DFG Str439/5-1), the Association Française contre les Myopathies (AFM), EU-IP ZF-HEALTH. Data The data shared in this article are the experimental ana

• GLPG0634 br Data Using TaqMan probes we have

  2018-11-03

  

  Data Using TaqMan probes we have previously established a real time RT-PCR method for Coxsackievirus A10 and other enterovirus detection [1]. The data presented in this article show the conserved regions for primers and probe design using multiple sequence alignment (Figs. 1 and 2). Table 1 repr

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