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Methods employed for distinguishing true thrombocytopenia fr
2018-11-12
Methods employed for distinguishing true thrombocytopenia from PTCP include using other anticoagulants (sodium citrate, oxalate, and heparin), elevating the temperature of a blood sample to 37°C, examining a blood sample containing EDTA as soon as possible, examining a blood smear under a microscope
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br Discussion IPNB is a papillary tumor containing
2018-11-12
Discussion IPNB is a papillary tumor containing biliary epithelium and grows within the bile duct. It can spread everywhere along the extra- and intrahepatic bile duct epithelium. IPNB has been categorized into a spectrum ranging from premalignant lesions to invasive cholangiocarcinomas. Intraduc
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To determine the time required for accurate
2018-11-12
To determine the time required for accurate viability assessment, approximately 1000 A. caninum eggs were transferred into 1.5mL centrifuge tubes, suspended in 1mL Phosphate Buffer Saline (PBS), and heat-inactivated on a heating block for 30min at 80°C. Tubes were centrifuged at 800× for 3min, and t
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Meng et al reported hESC culture using HEScGRO xeno free
2018-11-12
Meng et al. (2008) reported hESC culture using HEScGRO xeno-free complete culture medium from Millipore and a feeder layer from human foreskin fibroblasts. However, they maintained the hESC by mechanical passaging of the colonies. For rapid expansion of hESC cultures, transfection, and clonal select
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In contrast to the above the
2018-11-12
In ezh2 inhibitor to the above, the loose cell network in the +DAG group that was observed via histological staining may be a sign of reduced cell vitality. It is well known that cell death often leads to mineralization that is not combined with the formation of bone (Kirsch, 2006). Inorganic phosp
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Reprogrammation of CD cells from LRFs towards induced
2018-11-12
Reprogrammation of CD34+ nkcc inhibitor from LRFs towards induced pluripotent stem cells (iPS cells) could also be proposed and tested. Chou et al. (2011) and others cited by them succeeded in obtaining iPS cells from adult blood CD34+ cells without viral integration and showed that blood cells hav
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The information available regarding the effect of METH on
2018-11-12
The information available regarding the effect of METH on neurogenesis describes that, in the dentate gyrus (DG), cell proliferation is decreased in gerbils (postnatal day 30) administered once with the drug at postnatal day 14–20 (50mg/kg) (Hildebrandt et al., 1999). On the other hand, a lower dose
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br Materials and methods br
2018-11-12
Materials and methods Results and discussion Acknowledgments Introduction Reprogramming rejuvenates aged somatic cells back into the pluripotent state (Takahashi et al., 2007; Takahashi and Yamanaka, 2006). The developmental plasticity of induced pluripotent stem cells (iPSC) demonstrate
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Human DSTN and CFL are more than identical in
2018-11-12
Human DSTN and CFL1 are more than 70% identical in amino PyBOP cost sequence. DSTN has a much higher actin depolymerizing activity than Cofilin (Yeoh et al., 2002) which is explained by sequence differences at the F-actin-binding site (Pope et al., 2004). CFL1 deficiency is embryonic lethal at E11.5
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br Introduction Human embryonic and induced
2018-11-12
Introduction Human embryonic and induced pluripotent stem cells (h/iPSCs) are of considerable interest in developmental biology and regenerative medicine, representing an enormous opportunity for generating patient-specific cells for screening drugs and cell therapies for various diseases. Stem c
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Emerging evidence suggests that paracrine factor
2018-11-09
Emerging evidence suggests that paracrine factor profiling of MSCs is highly dependent on the microenvironment (Gao et al., 2016). Paracrine factors of iPSC-MSCs are reported to effectively rescue Dox-induced CM damage (Zhang et al., 2015). Nevertheless, how the therapeutic efficacy of MSCs is incre
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BM failure and leukemia at a young age
2018-11-09
BM failure and leukemia at a young age are the hallmarks of human FA patients, which made the study of FA of high interest for understanding the biology of HSC defect and malignant transformation. Mouse models have been developed for several FA fatty acid amide hydrolase (Parmar et al., 2009). Despi
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br Methods br Results br
2018-11-09
Methods Results Discussion Monitoring and early prediction of patient response to therapy is increasingly important, particularly because of heterogeneity of response to expensive or toxic agents, and missed opportunity of effective therapy by early switching. Many drugs, although targeted
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Furthermore such classification criteria that select a highl
2018-11-09
Furthermore, such classification criteria that select a highly specific sub-population of SS participants (those with 2 out of 3 objective signs - focus score≥1, positive serology, and ocular staining score≥3) (Shiboski et al., 2012) could challenge external validity. Therefore, clinical trial resul
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It has previously been hypothesised that iron
2018-11-09
It has previously been hypothesised that iron supplementation increases malaria susceptibility by increasing the availability of \'s preference for young RBCs (). observed significant shifts in RBC populations following iron supplementation, finding younger RBCs are most prevalent at Day 49 post iro
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