• Five year survival proportions for melanoma are poor for pat

  2018-10-23

  

  Five-year survival proportions for melanoma are poor for patients with metastatic disease, however if disease is detected in its early stages, then survival is one of the highest for all cancers. Even for those with metastases, survival differs depending on the extent of disease spread. Patients wit

• The important concept of crowdsourcing has been taken up

  2018-10-23

  

  The important concept of crowdsourcing has been taken up for market-based prediction markets, which operate with the additional benefit of a crowd-generated feedback signal or price, rather than a simple average. Evidence is mounting that prediction markets outperform not only the judgements of indi

• Vaccine studies conducted in both non human primate models A

  2018-10-23

  

  Vaccine studies conducted in both non-human primate models (Alpert et al., 2012; Gómez-Román et al., 2005; DeVico et al., 2007; Hidajat et al., 2009; Xiao et al., 2010; Brocca-Cofano et al., 2011; Barouch et al., 2012) and humans (Forthal et al., 2007; Haynes et al., 2012) have also suggested that A

• br Conflict of interest statement br Author contributions Th

  2018-10-23

  

  Conflict of interest statement Author contributions The following are the supplementary data related to this p-Cresyl sulfate article Acknowledgements We thank the NIAID Tetramer Facility (Emory University, Atlanta, GA) for supplying CD1d tetramer and Dr. T. Camou (National Reference Labo

• br Author contributions br Acknowledgements br Introduction

  2018-10-23

  

  Author contributions Acknowledgements Introduction Diabetes type 2 is an epidemic public health problem. Poorly controlled diabetes results in accelerated microvascular disease and chronic debilitating morbidities and mortality (Beckman et al., 2002). Diabetic microvascular angiopathy is th

• Today recent technological advances have dramatically

  2018-10-23

  

  Today, recent technological advances have dramatically improved the prospect of applying broadly the concept of precision medicine. Large-scale databases, omics technologies, cellular assays, epigenetics, informatics as well as imaging technologies converge towards optimum disease prevention, diagno

• Enteric bacteria have been implicated

  2018-10-23

  

  Enteric bacteria have been implicated in cancer progression of the gut (Louis et al., 2014; Schwabe and Jobin, 2013). Their increased abundance in bile duct tissues could promote tumorigenesis in a similar manner. Indeed, the data in this study supports an increase in the microbial production of ca

• We also noticed that there are statistically significant

  2018-10-23

  

  We also noticed that there are statistically significant differences in protein abundance levels depending on the season, or month, the samples were collected. After adjusting our protein abundance levels for storage time and individual age, we found only nominally significant associations with mont

• We also compared the protective

  2018-10-23

  

  We also compared the protective capacity of IgA2 mAb isoforms to their IgG1 counterparts following vaginal and rectal challenge. IgA2 can engage FcαR1 to mediate phagocytosis and ADCC via monocytes, Z DEVD FMK Supplier and neutrophils, and dimeric forms can aggregate HIV-1 virions (Woof and Russell

• br Human respiratory syncytial virus RSV is

  2018-10-23

  

  Human respiratory syncytial virus (RSV) is the most frequent cause of lower respiratory tract infections in infants and young children worldwide and also an important pathogen in elderly. Millions of patients get hospitalized and up to 200,000 children die each year due to an RSV infection (). Des

• The following are the supplementary data related to this

  2018-10-23

  

  The following are the supplementary data related to this article. Conflict of Interest Author Contributions Acknowledgments This work was supported by The Hormel Foundation and National Institutes of Health grants CA187027, CA027502, CA196639, and CA16601. We thank Dr. Robert H. Whitehead

• Another intriguing finding was that rs might modulate the

  2018-10-23

  

  Another intriguing finding was that rs12455792 might modulate the essential pathophysiological processes in TAAD-SMCs apoptosis, fibers accumulation and proteoglycans degradation, by fine tuning the SMAD4 expression. As we all known, the g protein coupled receptors is composed of 3 layers: tunica in

• Antigen Rv is a secretory antigen and a

  2018-10-23

  

  Antigen Rv0577 is a secretory antigen and a virulence factor associated with the replication of M. tuberculosis. The antigen is an agonist of Toll-like receptor 2 (TLR2) and can promote maturation of dendritic cells (Byun et al., 2012). Rv2875 encodes a cell membrane-associated antigen, MPT70, of M.

• br Experimental design materials and methods br

  2018-10-23

  

  Experimental design, materials and methods Conflicts of interest Acknowledgments This study was founded by grants from CNPq (Conselho Nacional do Desenvolvimento Científico e Tecnológico - process 302885/2011-0) and CAPES (Coordenação de Aperfeiçoamento de Pessoal de Nível Superior). Mirian

• br Data Xylogenesis a process of wood

  2018-10-23

  

  Data Xylogenesis (a process of wood fiber formation) is often characterized by two distinct stages: “early” and “late”. The first stage involves undifferentiated precursor order Tedizolid HCl that are characterized by their primary cell wall, whereas the later stage includes a succession of even

15002 records 997/1001 page Previous Next First page 上5页 9969979989991000 下5页 Last page