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SRT 1720 br Discussion Wellens reported an association betwe
2019-04-26
Discussion Wellens [1] reported an association between accessory pathways characterized by anterograde decremental conduction and the description of nodoventricular connections by Mahaim [2]. Consequently, these accessory pathways were erroneously referred to as “Mahaim pathways.” McClelland et a
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A first step forward would be to establish a
2019-04-26
A first step forward would be to establish a public-health-oriented commission or agency charged specifically with developing controls over the alcohol market and a strategy for reducing levels of alcohol consumption and problems, drawing on the strategies agreed on in the WHO Global Strategy for Re
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fexofenadine hydrochloride Almost all the information we hav
2019-04-26
Almost all the information we have on clinical epidemiology of patients with fexofenadine hydrochloride failure is collected in North America or in western European countriesTherefore, the work of Hisham Dokainish and colleagues in this issue of , is very welcome. Their study provides a clear pictu
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Paisey et al recently proposed a simple
2019-04-26
Paisey et al. recently proposed a simple technique for recognizing an MI block. In their study, an abrupt change of the CS activation pattern during RF application, under left atrial appendage pacing from a distal-to-proximal to proximal-to-distal direction provided a reliable assessment of MI condu
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Dexamethasone with its anti inflammatory properties has been
2019-04-26
Dexamethasone, with its anti-inflammatory properties, has been shown to be an effective medication in the treatment of pain flare and is hypothesized to prevent the phenomenon as well [12]. Despite a lack of literature investigating this hypothesis, currently published phase I and II trials have pro
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br Community based bundled health interventions
2019-04-25
Community-based bundled health interventions are complex and challenging to implement, monitor, and assess in informal settlements (slums). Such settlements in urban areas are generally characterised by congestion, squalid conditions, deprivation, violence, crime, and poor sanitation. In Asia and
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br Methods br Discussion This study demonstrated that upgrad
2019-04-24
Methods Discussion This study demonstrated that upgrading to CRT from RVAP improved cardiac performance and myocardial perfusion at pacing sites by SPECT. RVAP has been reported to alter left ventricular electrical and mechanical activation in a manner that is similar to the complete left bund
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Regarding the treatment of HLH with HLH the
2019-04-24
Regarding the treatment of HLH with HLH-1994, the estimated 3-year probability of survival overall was 55%. According to a previous comprehensive review study, ferritin level may provide a prognostic marker, and regular ferritin measurements may be useful in predicting outcomes in HLH patients. Our
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br OPG RANK and RANKL
2019-04-24
OPG, RANK and RANKL contribute to the vicious cycle established between tumour atipamezole and bone microenvironment: evidences for sarcomas and carcinomas RANK/RANKL axis is involved in the tumorigenic process RANK/RANKL axis is associated with the bone metastastic process, and as several arg
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stat3 pathway Numerous clinical trials phase II
2019-04-24
Numerous clinical trials (phase II and phase III) have been then designed to evaluate the efficacy of denosumab in oncology mainly in breast and prostate bone metastases (Table 1). These studies revealed that denosumab reduced significantly bone turnover markers similarly to osteoporotic patients. M
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citco br The role of other bone marrow cells
2019-04-24
The role of other bone marrow cells in metastatic cancer growth Other cell types also that take part in the regulation of the bone microenvironment, including myeloid and immune cells (T cells), platelets, bone marrow endothelial and haematopoietic cells, as well as bone marrow-derived mesenchyma
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Mechanistic target of rapamycin mTOR a highly conserved seri
2019-04-24
Mechanistic target of rapamycin (mTOR), a highly conserved serine-threonine protein kinase, is a key regulator of cell growth and metabolism. As discussed above, mTORC1 is a negative regulator of the preinitiation complex that modulates the initiation of autophagosome biogenesis. Pharmacological and
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The patient was consented to treatment on clinical
2019-04-23
The patient was consented to treatment on clinical trial NCT02527447 and received treatment with salvage chemotherapy of mitoxantrone 12mg/m2/day IV on days 1–3, etoposide 200mg/m2/day continuous IV infusion (CIV) on days 8–10, and cytarabine 500mg/m2/day CIV on days 1–3 and 8–10 (EMA). Infectious p
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Patients were divided randomly into two
2019-04-23
Patients were divided randomly into two groups at the time of hCG administration. Patients in Group 1 (n = 38; 33.6%) underwent IUI 24 hours after hCG administration. Group 2 (n = 75; 66.4%) underwent IUI 36 hours after hCG administration. All patients were instructed to have intercourse when the do
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The Millennium Development Goals MDGs have become
2019-04-23
The Millennium Development Goals (MDGs) have become key targets for the international purchase Cardiogenol C over the past 15 years. The MDGs have raised awareness, focused global efforts on agreed priorities, and empowered so-called development champions at country level. This progress was less str
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