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br Materials and methods Manganese chloride MnCl H
2022-06-06
Materials and methods Manganese chloride (MnCl2·4H2O), glutamate, glutamine, Lucifer Yellow, polyclonal anti-GFAP and MTT assay kits were purchased from Sigma Chemical Co. (St. Louis, MO). Dulbecco's Modified Eagle's Medium-F12 (DMEM-F12) with Earle's salts, foetal bovine serum, penicillin, and s
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br Galanin in depression A major
2022-06-06
Galanin in depression A major impediment in depression research is the lack of validated animals´ models. Animals not only lack consciousness of self, self-reflection and consideration of others but also hallmarks of the disorder such as depressed mood, low self-esteem or suicidal intent are hard
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Fas ligand FasL the natural ligand of Fas
2022-06-06
Fas ligand (FasL), the natural ligand of Fas, can interact with Fas and thus induce cell apoptosis through the cascade of death signal in various cell types [8]. Additionally, Fas, which is a member of the tumor necrosis factor (TNF) receptor superfamily and death receptor family, is one kind of tra
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br Introduction Before planning population based genetic ana
2022-06-06
Introduction Before planning population-based genetic analysis or GWAS, it is important to annotate the sequence of the gene because these sequences represent the major sites such as promoter and transcription factor eicosapentaenoic acid which may ultimately affect the expression of the gene. S
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br Nanoscale Cortical Actin Remodeling in Regulated Exocytos
2022-06-06
Nanoscale Cortical Actin Remodeling in Regulated Exocytosis The network of cortical acetaminophen paracetamol is formed by numerous fine actin filaments, which are only about 10nm in diameter [52]. Although the microscale role of the cortical actin network in vesicle exocytosis is well establishe
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br Discussion In our study the
2022-06-06
Discussion In our study the prevalence of severe periodontitis in patients with HIV infection was 66%, almost twice as high as in uninfected controls. Our results are in line with the prevalence of severe periodontitis found in HIV-infected patients in London, United Kingdom in the pre-cART era:
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Z-FA-FMK australia br Introduction Lysine acetylation is an
2022-06-06
Introduction Lysine acetylation is an important post-translational modification that is found on numerous cellular proteins, including both histone and non-histone proteins [1], [2]. Dynamic acetylation and deacetylation is regulated by enzymes called histone acetyltransferases (HATs) as writers
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br Materials and methods br Results
2022-06-05
Materials and methods Results Discussion Myocardium reperfusion injury contributes almost half of myocardial infarct size in myocardial infarction patients, and infarct size is closely correlated with the probability of developing ixabepilone failure [1]. Despite this knowledge, myocardial
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Different SVR rates have been observed when
2022-06-05
Different SVR rates have been observed when comparing GT 1a- and 1b-infected patients receiving BOC or TLP therapy. The response rates in patients infected with GT 1b have generally been more favourable than in those with GT 1a [26]. In our study, persistence mutations were only observed in HCV GT 1
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BADGE Although some PAHs that are human carcinogens have bee
2022-06-05
Although some PAHs that are human carcinogens have been found in the sugarcane soot (Zamperlini et al., 1997), there are no data about cancer incidence among sugarcane workers. To the best of our knowledge, this is the first report of an evaluation of internal exposure, comparing the harvesting (whe
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The present studies show that despite the
2022-06-05
The present studies show that, despite the high level of GSTP1-1 achieved in transfected cells, GSTP1-1 expression has no effect on sensitivities to the cytotoxicities of the oxazaphosphorines 4-OH-CP, 4-OOH-CP, and maf in MCF7 GSK2245840 synthesis (Fig. 4). The failure of GSTP1-1 to augment resist
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Although NO may act as
2022-06-05
Although, NO2− may act as the substrate for NO biosynthesis no strict correlation between NO2− fluctuation in roots and NO content was observed in tomato roots. As the culture period was prolonged NO2− concentration declined in control and m-Tyr exposed seedlings, and finally its concentration was s
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The recently de orphaned G protein coupled
2022-06-05
The recently de-orphaned G-protein coupled receptor (GPCR), GPR55, is activated endogenously by L-α-lysophosphatidylinositol (LPI), a lipid signaling molecule, as well as N-arachidonoyl glycine (NAGly) and numerous endo, phyto, and synthetic cannabinoids (Oka et al., 2007, Henstridge et al., 2010, H
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Notably we observed that GPR activation
2022-06-05
Notably, we observed that GPR35 activation induced by PA, an in vivo GPR35 agonist [6], significantly decreased DAI, colon weight, and histological score, while increasing colon length in mice with DSS-induced colitis. Furthermore, fibronectin and integrin α5 were co-localized with GPR35 on the colo
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In this study three potential Otx binding sites were
2022-06-05
In this study, three potential Otx-2 Pertussis Toxin synthesis were found in the promoter region of the sheep GnRH gene: −1786 bp to −1770 bp, −825 bp to −819 bp, and − 529 bp to −523 bp. Combined with the results of the double-luciferase assay, it could be inferred that the binding site of Otx-2 i
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